Padmanabham, a distinguished figure in Telugu cinema's comedy genre, entertained audiences for nearly three decades. He made his silver screen debut with "Mayalokam" (1945) and gained fame with the film "Shavukaru" (1949). He acted in numerous hit films like "Patala Bhairavi" , "Pelli Chesi Choodu" , "Chandraharam" , "Panduranga Mahatyam" , "Velugu Needalu" , "Doctor Chakravarty" , "Thene Manasulu" , "Potti Pleader" , "Sri Sri Sri Maryada Ramanna" , "Tikka Sankarayya" , "Sri Krishna Vijayamu" , "Desoddharakulu" , "Chanakya Chandragupta" , "Premabhishekam", and many more, totaling over 400 films. Not just a comedian, Padmanabham also ventured into directing and producing films such as "Devatha" , "Potti Pleader" , "Sri Sri Sri Maryada Ramanna" and "Kathanayika Molla." He directed films like "Shri Rama Katha" , "MidathamBotlu" , "Pellikani Thandri" and "Kathanayika Molla."